North Clin Istanb. 2019; 6(3): 315-316 | DOI: 10.14744/nci.2018.36539
Lansoprazole as an uncommon cause of anaphylaxis: What to give next?
, Sedat Bilge2
, Tolga Düzenli3
, Harun Aslan4
, Güçlü Aydın21
Department of Emergency Medicine, Acibadem Hospital, Istanbul, Turkey2
Department of Emergency Medicine, Gulhane Training and Research Hospital, Ankara, Turkey3
Department of Gastroenterology, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey4
Department of Internal Medicine, Koc University Hospital, Istanbul, Turkey
Proton pump inhibitors (PPIs) are one of the most prescribed drugs worldwide. Anaphylactic reactions of PPIs are rare; however, several cases have been reported. Here, we report a rare case of anaphylaxis that occurred immediately following lansoprazole intake. Following the successful management in the emergency department, skin prick and oral controlled challenge tests were performed to evaluate cross-reactivity. Thereafter, lansoprazole was switched to pantoprazole, which was well tolerated. Skin prick and oral controlled challenge tests can be performed for determining the cross-reactivity of PPIs to prevent adverse reactions.Keywords:
Anaphylaxis, cross-reactivity; lansoprazole; proton pump inhibitors.
Attila Aydın, Sedat Bilge, Tolga Düzenli, Harun Aslan, Güçlü Aydın. Lansoprazole as an uncommon cause of anaphylaxis: What to give next?. North Clin Istanb. 2019; 6(3): 315-316
Corresponding Author: Tolga Düzenli, Türkiye